Scientific Day 2024

Pilot Projects

EEG Workshop

Brain Dynamics Seminar Series

The Seminar Series takes place in the seminar room of the Paul Flechsig Institute, every second Friday at 12:00. It is envisaged to bring doctoral students, postdocs and PIs together and to facilitate the exchange of ideas within the scientific community.

enlarge the image: Im Vordergrund ist ein Mann von hinten zu sehen, der vor einem Rednerpult steht und einen Vortrag h?lt. Im unscharfen Hintergrund sitzen Zuschauer auf rot gepolsterten Stühlen.
Vortrag, Foto: Colourbox

past seminars

Prof Dr Dorothee Saur

Department of Neurology, University Hospital Leipzig

"Mapping mechanisms of reorganisation in the language network"
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PD Dr Markus Schwab

Paul Flechsig Institute of Neuropathology, University Hospital Leipzig

"Molecular regulation of neural networks: from the nucleus to axon and synapse"
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Dr Lars Meyer

Max Planck Research Group Language Cycles, MPI for Human Cognitive and Brain Sciences, Leipzig & Clinic for Phoniatrics and Pedaudiology, University Hospital Münster

"Interdisciplinary Research on Language: Behavioural, Electrophysiological, and Computational Tools"
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Prof Dr Stefan Schmukle

Wilhelm Wundt Institute for Psychology, Faculty of Life Sciences, University Leipzig

"Research on Interindividual Differences"
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Prof Dr Robert Kittel

Department of Animal Physiology, Faculty of Life Sciences, University Leipzig

"In search of active zone engrams"
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Dr Falk Eippert

Max Planck Research Group Pain Perception, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig

"Non-invasive approaches to study human spinal cord function"
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Dr Nicole Scholz

Rudolf Sch?nheimer Institute of Biochemistry, Faculty of Medicine, University Leipzig

"Adhesion GPCR-mediated signaling across cells"
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Dr Bilal Sheikh

Helmholtz Institute for Metabolic, Obesity and Vascular Research (Hl-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig

"Dissecting neurovascular function in health and disease"
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20.01. Dr Alexander Jais
Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig
"Prepronociceptin-expressing neurons induce overeating and mediate energy expenditure"

03.02. Prof Dr Gesa Hartwigsen
Cognitive and Biological Psychology, Wilhelm Wundt Institute, Leipzig University & Lise Meitner Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences (MPI CBS), Leipzig
"Short-term plasticity in neural networks for cognition – insights from healthy young, aging, and lesioned brains"

03.03. Prof Dr Stefan Hallermann
Carl Ludwig Institute of Physiology, Faculty of Medicine, Leipzig
"Ketamine boosts presynaptic release at a central glutamatergic synapse"

17.03. Prof Dr Anja Widdig
Institute of Biology, Faculty of Life Sciences & Department of Human Behaviour, Ecology and Culture, MPI for Evolutionary Anthropology, Leipzig
"The impact of realized relatedness on the evolution of primate sociality based on WGS data"

31.03. Dr Christian Simon
Carl Ludwig Institute of Physiology, Faculty of Medicine, Leipzig
"Motor neurons drive motor circuit pathology in a distal form of spinal muscular atrophy"

21.04. Prof Dr Mareike Zink
Peter Debye Institute for Soft Matter Physics, Faculty of Physics and Earth Sciences, Leipzig
"How to study biocompatibility of neuroelectrodes with biophysical tools and machine-learning algorithms"

05.05. Prof Dr Marc Sch?nwiesner
Institute of Biology, Faculty of Life Sciences, Leipzig & Department of Psychology, University of Montreal, Quebec, Canada
"Spatial hearing: brain plasticity, wearable technology, and the best home stereo system ever built"

26.05. Dr Kristina Lippmann
Carl Ludwig Institute of Physiology, Faculty of Medicine, Leipzig
"Hippocampal network oscillations are shaped by activated ATP-sensitive potassium channels of fast-spiking interneurons"

09.06. Prof Dr Matthias Müller
Wilhelm Wundt Institute of Psychology, Faculty of Life Sciences, Leipzig
"Frequency-tagged stimuli uncover basic neural mechanisms of feature-based attention in the human brain"

23.06. Prof Dr Rami Abou Jamra
Institute of Human Genetics, University Hospital Leipzig
"2000 trio exome sequencing on research base: output and outlook"

07.07. Prof Dr Swen Hesse
Department of Nuclear Medicine, University Hospital Leipzig
"Neuroreceptors at work: in vivo molecular imaging of neutrotransmission in humans with SPECT and PET"

03.11. PD Dr Dennis Pauls
Department of Animal Physiology, Faculty of Life Sciences, Leipzig
"Neurophysiological mechanisms of feeding decisions"

17.11. Prof Dr Hartmut Schmidt
Carl Ludwig Institute of Physiology, Faculty of Medicine, Leipzig
"Transmitter release from neocortical synapses: Ca2+-sensitivity, area-specificity and regulation"

01.12. Prof Dr Dr Markus Morawski
Paul Flechsig Institute of Brain Research, Faculty of Medicine, Leipzig
"Potential function of perineuronal nets in the CNS"

11.03. Prof. Dr. Katja Liebal
Human Biology & Primate Cognition, Faculty of Life Sciences, University Leipzig
"The value of a comparative approach to understand human cognition and behavior"

25.03. Prof. Dr. Ruth Stassart
Remyelination and Nerve Repair, Paul Flechsig Institute of Neuropathology, University Hospital Leipzig
"Repair strategies in diseases of the peripheral nervous system"

08.04. Prof. Dr. Ingo Bechmann
Institute of Anatomy, Medical Faculty, University Leipzig
"Microglia: Population control and aging"

22.04. PD Dr. Philipp Gunz
Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig
"What Neanderthals have to say about your brain"

20.05. Prof. Dr. D. Phil. (Oxon) Tobias Langenhan
Rudolf Sch?nheimer Institute of Biochemistry, Medical Faculty, University Leipzig
"Molecular signalling at and across the synapse"

03.06. Prof. Dr. Andreas S. Thum
Department of Genetics, Faculty of Life Sciences, University Leipzig
"From structure to function: what we can learn from the connectome of the Drosophila larva"

17.06. Prof. Dr. Christian Doeller
Department of Psychology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig
"Structuring Experience in Cognitive Spaces"

01.07. Prof. Dr. Tamara Tal
Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig
"Using zebrafish larvae to understand chemical phenotypes, mechanisms, and the microbiome"

14.10. Dr. Robert Fledrich
Institute of Anatomy, Medical Faculty, University Leipzig
"Metabolic implications of myelin repair"

04.11. Prof. Dr. Martin Bogdan
Department of Neuromorphic Information Processing, Faculty of Mathematics and Computer Science, University Leipzig
"From artificial neural networks and machine learning to neuromorphic information processing: The next generation of AI?"

18.11. Prof. Dr. Thomas Arendt
Paul Flechsig Institute of Brain Research, Medical Faculty, University Leipzig
"An evolutionary and developmental perspective on Alzheimer?s disease"

02.12. PD Dr. Veronica Witte
Department of Neurology, MPI for Human Cognitive and Brain Sciences & Cognitive Neurology, University Hospital, Leipzig
"Impact of obesity and diet on brain structure and function: a gut–brain–body crosstalk"

16.12. Prof. Dr. Sebastian Grüneisen
Leipzig Research Center for Early Child Development, Faculty of Education, University Leipzig
"Coordinated decision-making in young children"

Open Lab Day

Have a peek into a typical lab day of a research group of the Brain Dynamics Graduate School.

enlarge the image: Foto: Ein Student der Biowissenschaften in einem Kittel gekleidet und mit blauen Fü?lingen sitzt am Schreibtisch eines Labors
Student der Biowissenschaft im Labor, Foto: Christian Hüller

Open labs 2024

Research Group Simon

Carl Ludwig Institute of Physiology, Medical Faculty, University Leipzig

"Motor neuron diseases and methods"
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Research Group Sch?nwiesner

Institute of Biology, Faculty of Life Sciences, University Leipzig

"Spatial hearing in different acoustic environments"
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Latest News

Latest News

Brain Dynamics Pilot Projects

Open call for collaborative project proposals

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NeuroDoWo 2024

Day tickets available for the Neurobiology Doctoral Students Workshop taking place in Leipzig on August 20th - 23rd

register now

Brain Dynamics Science Speed Dating

The third informal meeting of the Brain Dynamics members will be held on 29th May

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Congratulations to Dr Lamberty

Another Brain Dynamics member successfully defended his doctoral thesis

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Pilot Project grants awarded

Five collaborative projects by Brain Dynamics members to receive funding

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Scientific Day 2023

Annual meeting of the Brain Dynamics Graduate School held on 28th September

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Brain Dissection

Crash Course on Brain Anatomy by Prof. Ingo Bechmann

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Microscopy course

A course in light and electron microscopy for doctoral and postdoctoral researchers

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TAC experiences

Doctoral students talk about the advantages of having a Thesis Advisory Committee (TAC)

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Upcoming and past events

David C. Martinelli

12.09. 14:00 Online + Beckmann Lecture Hall, Institute of Biochemistry - "The pleiotropic C1Q-like proteins regulate both synapses and oligodendrocyte maturation"

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Jeroen Bogie

09.09. 10:30 Seminar Room 3093, PFI - "Lipids in control of microglia physiology in demyelinating CNS disorders"

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Maya Inbar

04.09. 13:00 Online + Wilhelm Wundt Room (A400), MPI CBS - "The temporal structure of intonation units in spontaneous speech: cross-linguistic and neuroscientific investigations"

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Omega Lab Mini-Symposium

02.09. 09:00-11:30 Online + Wilhelm Wundt Room (A400), MPI CBS - "Exploring the gut-brain interplay"

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Summer Symposium

21.08. 15:00-18:00 Kleiner H?rsaal, Institute of Biology - Dr Shiqiang Gao, Prof Dr Susanne Schoch, Dr Giorgio Gilestro

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Lucia Melloni

17.06. 16:00 Online - "Using Adversarial Collaboration to Harness Collective Intelligence"

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Dorothee Saur

14.06. 12:00 Seminar Room 3093, PFI - "Mapping mechanisms of reorganisation in the language network"

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  • 10.10.2024 15:30 Faculty of Medicine
  • Regina Tina Jentzsch
    Wenn aus W?rtern Welten werden – Situationsmodellbildung beim Textverstehen von gesunden Erwachsenen und Patienten nach Sch?del-Hirn-Trauma”
  • Josefine Jentzsch
    Zusammenhang subjektiver kognitiver Verschlechterung, objektiver Ged?chtnisleistung und Hippocampusvolumen bei ?lteren Menschen mit kardiovaskul?rem Risikoprofil für die Entwicklung einer Alzheimer-Krankheit”
  • Anne Edwina Kullek
    The role of macrophages in Charcot-Marie-Tooth disease type 1A”
  • Fabian Kropla
    Personalisierte Neurochirurgie durch den Einsatz Additiver Fertigung??"
  • For more information click here.

Scientific publications

Latest Publications by Brain Dynamics doctoral candidates

Klingbeil J, Mühlig M, Bahr E, Welle F, Ritter T, Stockert A, Wawrzyniak M, Saur D.
Undoubtedly unaware of homonymous hemianopia: The contribution of overconfidence to anosognosia of hemianopia.
Cortex. 2024 Aug; 177: 224-234.

Gutsfeld S, Wehmas L, Omoyeni I, Schweiger N, Leuthold D, Michaelis P, Howey XM, Gaballah S, Herold N, Vogs C, Wood C, Bertotto L, Wu GM, Klüver N, Busch W, Scholz S, Schor J, Tal T.
Investigation of Peroxisome Proliferator-Activated Receptor Genes as Requirements for Visual Startle Response Hyperactivity in Larval Zebrafish Exposed to Structurally Similar Per- and Polyfluoroalkyl Substances (PFAS).
Environ Health Perspect. 2024 Jul; 132(7): 77007.

Tast V, Schr?ger E, Widmann A.
Suppression and omission effects in auditory predictive processing-Two of the same?
Eur J Neurosci. 2024 May 19. doi: 10.1111/ejn.16393.

Burkart ME, Kurzke J, Jacobi R, Vera J, Ashcroft FM, Eilers J, Lippmann K.
KATP channel mutation disrupts hippocampal network activity and nocturnal gamma shifts.
Brain. 2024 May 15; awae157.

Bullmann T, Kaas T, Ritzau-Jost A, W?hner A, Kirmann T, Rizalar FS, Holzer M, Nerlich J, Puchkov D, Geis C, Eilers J, Kittel RJ, Arendt T, Haucke V, Hallermann S.
Human iPSC-derived neurons with reliable synapses and large presynaptic action potentials.
J Neurosci. 2024 May 9: e0971232024.

Upadhya M, Kirmann T, Wilson MA, Simon CM, Dhangar D, Geis C, Williams R, Woodhall G, Hallermann S, Irani SR, Wright SK.
Peripherally-derived LGI1-reactive monoclonal antibodies cause epileptic seizures in vivo.
Brain. 2024 Apr 25: awae129.

Richter V, Rist A, Kislinger G, Laumann M, Schoofs A, Miroschnikow A, Pankratz M, Cardona A, Thum AS.
Morphology and ultrastructure of external sense organs of Drosophila larvae.
eLife 12: RP91155.

Vieira Contreras F, Auger GM, Müller L, Richter V, Huetteroth W, Seufert F, Hildebrand PW, Scholz N, Thum AS, Ljaschenko D, Blanco-Redondo B, Langenhan T.
The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila.
Cell Rep. 2024 Jan 4; 43(1): 113640. doi: 10.1016/j.celrep.2023.113640.

Simon M, Widdig A, Wei? BM.
Sniffing behavior of semi free-ranging Barbary macaques (Macaca sylvanus).
Am J Primatol. 2024 Feb 26: e23611. doi: 10.1002/ajp.2361

Past publications

  • Sundaram VK, Schütza V, Schr?ter NH, Backhaus A, Bilsing A, Joneck L, Seelbach A, Mutschler C, Gomez-Sanchez JA, Sch?ffner E, Sánchez EE, Akkermann D, Paul C, Schwagarus N, Müller S, Odle A, Childs G, Ewers D, Kungl T, Sitte M, Salinas G, Sereda MW, Nave KA, Schwab MH, Ost M, Arthur-Farraj P, Stassart RM, Fledrich R.
    Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration.
    Cell Metab. 2023 Dec 5; 35(12): 2136-2152.e9. doi: 10.1016/j.cmet.2023.10.017.

  • Moceri S, B?uerle N, Habermeyer J, Ratz-Wirsching V, Harrer J, Distler J, Schulze-Krebs A, Timotius IK, Bluhm A, Hartlage-Rübsamen M, Ro?ner S, Winkler J, Xiang W, H?rsten SV.
    Young human alpha synuclein transgenic (BAC-SNCA) mice display sex- and gene-dose-dependent phenotypic disturbances.
    Behav Brain Res. 2023 Dec 1: 114781. doi: 10.1016/j.bbr.2023.114781.

  • Mustapha O, Grochow T, Olopade J, Fietz SA.
    Neocortex neurogenesis and maturation in the African greater cane rat.
    Neural Dev. 2023 Oct 13; 18(1): 7. doi: 10.1186/s13064-023-00175-x.

  • Gundlach C, Wehle S, Müller MM.
    Early sensory gain control is dominated by obligatory and global feature-based attention in top-down shifts of combined spatial and feature-based attention.
    Cereb Cortex. 2023 Sep; 33(19): 10286-10302.

  • Seufert F, Chung YK, Hildebrand PW, Langenhan T.
    7TM domain structures of adhesion GPCRs: what's new and what's missing?
    Trends Biochem Sci. 2023 Aug; 48(8): 726-739.

  • Sch?ffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strau? J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, M?bius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich R, Nave KA, Stassart RM.
    Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease.
    Nat Neurosci. 2023 Jul; 26(7): 1218-1228.

  • Wender M, Bornschein G, Brachtendorf S, Hallermann S, Eilers J, Schmidt H.
    Cav2.2 channels sustain vesicle recruitment at a mature glutamatergic synapse.
    J Neurosci. 2023 Apr; JN-RM-1279-22.

  • Kong L, Hassinan CW, Gerstner F, Buettner JM, Petigrow JB, Valdivia DO, Chan-Cortés MH, Mistri A, Cao A, McGaugh SA, Denton M, Brown S, Ross J, Schwab MH, Simon CM, Sumner CJ.
    Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation.
    Acta Neuropathol Commun. 2023 Mar; 11(1): 53.

  • Anglada-Tort M, Harrison PMC, Lee H, Jacoby N.
    Large-scale iterated singing experiments reveal oral transmission mechanisms underlying music evolution.
    Curr Biol. 2023 Mar; S0960-9822(23)00243-9.

  • Scholz N, Dahse AK, Kemkemer M, Bormann A, Auger GM, Vieira Contreras F, Ernst LF, Staake H, K?rner MB, Buhlan M, Meyer-M?lck A, Chung YK, Blanco-Redondo B, Klose F, Jarboui MA, Ljaschenko D, Bigl M, Langenhan T.
    Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation.
    Nature. 2023 Mar.

  • Streit M, Hemberger M, H?fner S, Knote F, Langenhan T, Beliu G.
    Optimized genetic code expansion technology for time-dependent induction of adhesion GPCR-ligand engagement.
    Protein Sci. 2023 Mar; e4614.

  • Steinke S, Kirmann T, Loi EA, Nerlich J, Weichard I, Kuhn P, Bullmann T, Ritzau-Jost A,
    Rizalar FS, Prüss H, Haucke V, Geis C, Hust M, Hallermann S.
    NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies.
    Brain. 2023 Mar; awac497.

  • Schulz A, Richter F, Richter A.
    In vivo optogenetic inhibition of striatal parvalbumin-reactive interneurons induced genotype-specific changes in neuronal activity without dystonic signs in male DYT1 knock-in mice.
    J Neurosci Res. 2023 Apr; 101(4): 448-463.

  • Hennlein L, Ghanawi H, Gerstner F, Palominos García E, Yildirim E, Saal-Bauernschubert L, Moradi M, Deng C, Klein T, Appenzeller S, Sauer M, Briese M, Simon C, Sendtner M, Jablonka S.
    Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy.
    J Cell Biol. 2023 Mar; 222(3): e202204113.

  • Schlensog-Schuster F, Keil J, Von Klitzing K, Gniewosz G, Schulz CC, Schlesier-Michel A, Mayer S, Stadelmann S, D?hnert M, Klein AM, Sierau S, Manly JT, Sheridan MA, White LO.
    From Maltreatment to Psychiatric Disorders in Childhood and Adolescence: The Relevance of Emotional Maltreatment.
    Child Maltreat. 2022 Nov; 10775595221134248.

  • Klein CC, Berger P, Goucha T, Friederici AD, Grosse Wiesmann C.
    Children's syntax is supported by the maturation of BA44 at 4 years, but of the posterior STS at 3 years of age.
    Cereb Cortex. 2022 Nov; bhac430.

  • Buettner JM, Sowoidnich L, Gerstner F, Blanco-Redondo B, Hallermann S, Simon CM.
    p53-dependent c-Fos expression is a marker but not executor for motor neuron death in spinal muscular atrophy mouse models.
    Front Cell Neurosci. 2022 Nov; 16: 1038276.

  • Perl S, Lüttig A, K?hling R, Richter A.
    Deep brain stimulation in animal models of dystonia.
    Neurobiol Dis. 2022 Oct; 175: 105912.

  • Bluhm A, Schrempel S, Moceri S, Stieler J, Feja M, Schilling S, Schulze A, von H?rsten S, Hartlage-Rübsamen M, Richter F, Ro?ner S.
    Alpha synuclein processing by MMP-3 - implications for synucleinopathies.
    Behav Brain Res. 2022 Sep; 434: 114020.

  • Becker S, Schulz A, Kreyer S, Dre?ler J, Richter A, Helmschrodt C.
    Sensitive and simultaneous quantification of 16 neurotransmitters and metabolites in murine microdialysate by fast liquid chromatography-tandem mass spectrometry.
    Talanta. 2022 Sep; 253: 123965.

  • Schulz CC, von Klitzing K, Deserno L, Sheridan MA, Crowley MJ, Schoett MJS, Hoffmann F, Villringer A, Vrti?ka P, White LO.
    Emotional maltreatment and neglect impact neural activation upon exclusion in early and mid-adolescence: An event-related fMRI study.
    Dev Psychopathol. 2022 May; 34(2): 573-585.

  • Buettner JM, Kirmann T, Mentis GZ, Hallermann S, Simon CM.
    Laser microscopy acquisition and analysis of premotor synapses in the murine spinal cord.
    STAR Protoc. 2022 Mar; 3(1): 101236.

  • Ruthig P, Sch?nwiesner M.
    Common principles in the lateralization of auditory cortex structure and function for vocal communication in primates and rodents.
    Eur J Neurosci. 2022 Feb; 55(3): 827-845.

  • Braga A, Sch?nwiesner M.
    Neural Substrates and Models of Omission Responses and Predictive Processes.
    Front Neural Circuits. 2022 Feb; 16: 799581.

Further reading

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Contact

Dr. Sa?a Jovanovic

Scientific Coordinator

Institutsgeb?ude
Talstra?e 33, Room 332
04103 Leipzig

Phone: +49 341 97 - 36740
Fax: +49 341 97 - 36749

Office hours
Montag - Freitag 09:00 - 16:00